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Differential Synaptic Loss in β-Amyloid Positive Versus β-Amyloid Negative Corticobasal Syndrome.

Negin HollandGeorge SavulichP Simon JonesDavid J WhitesideDuncan StreetPeter SwannMichelle NaessensMaura MalpettiYoung T HongTim D FryerTimothy RittmanEoin MulroyFranklin I AigbirhioKailash P BhatiaJohn T O'BrienJames Benedict Rowe
Published in: Movement disorders : official journal of the Movement Disorder Society (2024)
F]AV-1451 binding and gray matter volume loss, indicate differences in the pathogenic mechanisms of CBS according to whether it is associated with the presence of Alzheimer's disease or not. This highlights the potential for different therapeutic strategies in CBSs. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • cognitive decline
  • case report
  • human health
  • dna binding
  • risk assessment
  • prefrontal cortex