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Ureaplasma urealyticum osteomyelitis of the greater trochanter in a patient with multiple sclerosis using ocrelizumab - a case report.

Fred RuythoorenStijn GhijselingsMelissa DepypereWillem-Jan MetsemakersLiesbet HenckaertsNathalie NoppeGeorges Vles
Published in: Journal of bone and joint infection (2024)
Ocrelizumab - a monoclonal anti-CD20 antibody used in treatment of multiple sclerosis (MS) - marks significant progress in treating autoimmune diseases but raises susceptibility to opportunistic infections due to hypogammaglobulinemia. A young MS patient developed osteomyelitis from persistent Ureaplasma urealyticum urethritis, which was diagnosed with specialized polymerase chain reaction and resolved with targeted antibiotics. A multidisciplinary approach is crucial for managing such infections.
Keyphrases
  • multiple sclerosis
  • white matter
  • case report
  • mass spectrometry
  • palliative care
  • cancer therapy
  • middle aged
  • drug delivery
  • quality improvement
  • combination therapy
  • smoking cessation