Brain interstitial glycerol correlates with evolving brain injury in paediatric traumatic brain injury.
Nqobile S ThangoUrsula K RohlwinkLindizwe DlaminiM Phophi TshavhungweE BanderkerShamiel SalieJ M N EnslinAnthony A FigajiPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2021)
This is the first study to provide data on brain interstitial glycerol in children. CMD glycerol, particularly an increase from baseline, is associated with other markers of injury and with a significant increase in lesion size on repeat head CT. As such, it may represent a useful monitorable marker for evolving injury in paediatric TBI.
Keyphrases
- brain injury
- traumatic brain injury
- cerebral ischemia
- subarachnoid hemorrhage
- intensive care unit
- resting state
- white matter
- emergency department
- young adults
- functional connectivity
- computed tomography
- electronic health record
- contrast enhanced
- severe traumatic brain injury
- multiple sclerosis
- positron emission tomography
- machine learning
- data analysis
- artificial intelligence