Late responses in the anterior insula reflect the cognitive component of pain: evidence of nonpain processing.
Nami TaniguchiNaruhito HironagaTakako MitsudoShunsuke TamuraKen YamauraShozo TobimatsuPublished in: Pain reports (2022)
The current findings suggested that late AI activation reflects the processing of cognitive pain information, whereas the PI and early AI responses reflect sensory processing.