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Static spatial growth restriction micropatterning of endothelial colony forming cells influences their morphology and gene expression.

Matthew W HagenMonica T Hinds
Published in: PloS one (2019)
Endothelial colony forming cells can be durably micropatterned using spatial growth restriction. Micropatterning has a significant effect on the gross and subcellular morphologies of both cell types. Further study is required to fully understand the effect of micropatterning on endothelial colony forming cell gene expression.
Keyphrases
  • gene expression
  • induced apoptosis
  • cell cycle arrest
  • endothelial cells
  • dna methylation
  • single cell
  • cell therapy
  • endoplasmic reticulum stress
  • cell death
  • stem cells
  • cell proliferation