Concurrent immune checkpoint inhibition and selective immunosuppressive therapy in patients with immune-related enterocolitis.

Yousef R BadranFangwen ZouSienna M DurbinBarbara E DutraHamzah Abu-SbeihAnusha S ThomasMehmet AltanJohn A ThompsonWei QiaoDonna E LeetPo-Ying LaiNora K HorickMichael A Postow David M Faleck Yinghong Wang Michael L Dougan

Published in: Journal for immunotherapy of cancer (2023)

After resolution of irEC symptoms, reinitiation of ICI with concurrent SIT is safe, reduces severe irEC recurrence, and has no negative impact on survival outcomes.

Keyphrases

locally advanced
early onset
low birth weight
free survival
single molecule
drug induced
sleep quality
preterm infants
physical activity