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A generative model of hyperelastic strain energy density functions for multiple tissue brain deformation.

Alejandro Granados MartinezFernando Perez-GarciaMartin SchweigerVejay VakhariaSjoerd B VosAnna MiserocchiAndrew W McEvoyJohn S DuncanRachel SparksSébastien Ourselin
Published in: International journal of computer assisted radiology and surgery (2020)
Our generative model can capture uncertainties related to mechanical characterisation of tissue. When fitting samples from elastography and linear studies, all meta-models performed similarly. The Ogden meta-model performed the best on hyperelastic studies. We were able to predict elastic parameters in a reference model on a synthetic phantom. However, deformation observed in clinical cases is only partly explained using our generative model.
Keyphrases
  • magnetic resonance imaging
  • brain injury
  • blood brain barrier
  • case control
  • image quality
  • dual energy