CRF1 Receptor-Dependent Increases in Irritability-Like Behavior During Abstinence from Chronic Intermittent Ethanol Vapor Exposure.
Adam KimbroughGiordano de GuglielmoJenni KononoffMarsida KallupiEric P ZorrillaOlivier GeorgePublished in: Alcoholism, clinical and experimental research (2017)
Irritability-like behavior is a clinically relevant and reliable measure of negative emotional states that is partially mediated by activation of the CRF-CRF1 system and remains elevated during protracted abstinence in ethanol-dependent rats.
Keyphrases