Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn.

Kenneth Jpseph MoiseLeona E LingDick OepkesEleonor TibladE J T Joanne VerweijEnrico LoprioreJohn SmoleniecUlrich J SachsGregor BeinMark David KilbyRussell S MillerRoland DevliegerFrançois AudibertStephen P EmeryKara MarkhamMary E NortonOlga Ocón-HernándezPranav PandyaLeonardo PereiraRobert M SilverRory WindrimJames B StreisandJocelyn H LeuArpana MirzaValerie SmithLisa B SchwartzMay Lee TjoaShumyla Saeed-KhawajaYosuke KomatsuJames B Busselnull null

Published in: The New England journal of medicine (2024)

Nipocalimab treatment delayed or prevented fetal anemia or intrauterine transfusions, as compared with the historical benchmark, in pregnancies at high risk for early-onset severe HDFN. (Funded by Janssen Research and Development; UNITY ClinicalTrials.gov number, NCT03842189.).

Keyphrases

early onset
late onset
preterm birth
gestational age
combination therapy
pregnancy outcomes