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Divergent process for the catalytic decarboxylative thiocyanation and isothiocyanation of carboxylic acids promoted by visible light.

Jordan VigierMélissa GaoPhilippe JubaultHélène LebelTatiana Besset
Published in: Chemical communications (Cambridge, England) (2023)
A divergent photoinduced selective synthesis of thiocyanate and isothiocyanate derivatives from readily available carboxylic acids was developed using N -thiocyanatosaccharin and a catalytic amount of base or acid. This molecular editing strategy allowed the functionalization of bioactive compounds. A mechanism for the transformation was proposed based on control experiments.
Keyphrases
  • visible light
  • crispr cas
  • crystal structure
  • single molecule
  • transition metal