The impact of cholesterol deposits on the fibrillar architecture of the Achilles tendon in a rabbit model of hypercholesterolemia.
Andrzej SteplewskiJolanta FertalaRyan TomlinsonKevth'er HoxhaLin HanOcean ThakarJason KleinJoseph AbboudAndrzej FertalaPublished in: Journal of orthopaedic surgery and research (2019)
Our findings support the hypothesis that hypercholesterolemia coincides with the weakening of the tendons. It is likely that the intimate contact between collagen fibrils and cholesterol deposits contributes to the weakening of the fibrillar structure of the tendons.