Infectious Complications in Laparoscopic Gynecologic Oncology Surgery within an ERAS-Compliant Setting.
Vito Andrea CapozziAlessandra De FinisElisa ScarpelliAsya GallinelliLuciano MonfardiniStefano CianciFerdinando Antonio GulinoIsabella RotondellaGabriella Maria CeloraGiulia MartignonTullio GhiRoberto BerrettaPublished in: Journal of personalized medicine (2024)
Minimally Invasive Surgery (MIS) represents a safe and feasible option for the surgical treatment of gynecologic malignancies, offering benefits, including reduced blood loss, lower complications, and faster recovery, without compromising oncological outcomes in selected patients. MIS is widely accepted in early-stage gynecologic malignancies, including endometrial cancer, cervical tumors measuring 2 cm or less, and early-stage ovarian cancer, considering the risk of surgical spillage. Despite its advantages, MIS does not rule out the possibility of adverse events such as postoperative infections. This retrospective study on 260 patients undergoing laparoscopic surgery at Parma University Hospital for gynecologic malignancies explores the incidence and risk factors of postoperative infectious complications. The Clavien-Dindo classification was used to rank postoperative surgical complications occurring 30 days after surgery and Enhanced Recovery After Surgery (ERAS) recommendations put into practice. In our population, 15 (5.8%) patients developed infectious complications, predominantly urinary tract infections (9, 3.5%). Longer surgical procedures were independently associated with higher postoperative infection risk ( p = 0.045). Furthermore, C1 radical hysterectomy correlated significantly with infectious complications ( p = 0.001, OR 3.977, 95% CI 1.370-11.544). In conclusion, compared to prior research, our study reported a lower rate of infectious complications occurrence and highlights the importance of adopting infection prevention measures.
Keyphrases
- patients undergoing
- endometrial cancer
- early stage
- risk factors
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- prognostic factors
- prostate cancer
- healthcare
- urinary tract infection
- laparoscopic surgery
- peritoneal dialysis
- primary care
- type diabetes
- acute coronary syndrome
- minimally invasive
- robot assisted
- percutaneous coronary intervention
- radiation therapy
- coronary artery bypass
- radical prostatectomy
- weight loss
- coronary artery disease
- patient reported
- sentinel lymph node
- surgical site infection
- neoadjuvant chemotherapy