Evaluation of myostatin as a possible regulator and marker of skeletal muscle-cortical bone interaction in adults.
Nagato KuriyamaEtsuko OzakiTeruhide KoyamaDaisuke MatsuiIsao WatanabeSatomi TomidaReo NagamitsuKanae HashiguchiMasaaki InabaShinsuke YamadaMotoyuki HoriiShigeto MizunoYutaro YonedaMasao KurokawaDaiki KobayashiShinpei FukudaKoichi IwasaYoshiyuki WatanabeRitei UeharaPublished in: Journal of bone and mineral metabolism (2020)
A decrease in cortical bone thickness was associated with a decrease in skeletal muscle mass accompanied by an increase in the blood myostatin level. Blood myostatin may regulate the bone-skeletal muscle relationship and serve as a surrogate marker of bone metabolism, potentially linking muscle mass to bone structure.