Sodium Oxybate in Treatment-Resistant REM Sleep Behavior Disorder.

Emmanuel H DuringBeatriz HernandezMitchell G MiglisOliver Sum-PingAnahid HekmatAna CahuasAdrian EkelmansFuyumi YoshinoEmmanuel Jean-Marie Mignot Clete A Kushida

Published in: Sleep (2023)

SXB could reduce RBD symptoms; however, response was inconsistent and a large placebo effect was observed across patient-reported outcomes. Larger studies using objective endpoints are needed.

Keyphrases

patient reported outcomes
sleep quality
physical activity
case control
double blind
phase iii
study protocol