Exploring the level of agreement among different drug-drug interaction checkers: a comparative study on direct oral anticoagulants.

Massimo Carollo Salvatore Crisafulli Francesco Ciccimarra Giuseppe Andò Igor Diemberger Gianluca Trifirò

Published in: Expert opinion on drug metabolism & toxicology (2024)

The heterogeneity among different ICs and SPCs underscores the need to standardize DDI datasets and to conduct real-world studies to generate evidence regarding the frequency and clinical relevance of potential DOAC-related DDIs.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
drug induced
single cell
case control
human health
risk assessment