Should chromosomal microarray be offered to fetuses with ultrasonographic soft markers in second trimester: A prospective cohort study and meta-analysis.

Shuyuan LiXu HanMujin YeSongchang ChenYinghua ShenJianmei NiuYanlin WangXian-Ling Cao

Published in: Prenatal diagnosis (2020)

It is reasonable to offer CMA as a first-tier test to fetuses with MVM. However, for fetuses with other USMs, the considerations to perform CMA should not differ from pregnancies with normal ultrasound.

Keyphrases

gestational age
preterm birth
magnetic resonance imaging
gene expression
pregnancy outcomes
ultrasound guided
copy number
pregnant women
contrast enhanced ultrasound
optic nerve