Does non-invasive prenatal testing affect the livebirth prevalence of Down syndrome in the Netherlands? A population-based register study.
Maurike Dorothea de Groot-van der MoorenGert de GraafMichel E WeijermanMariette J V HofferJeroen KnijnenburgAnne-Marie M F van der Kevie-KersemaekersAngelique J A KooperEls VoorhoeveBirgit Sikkema-RaddatzLaura J C M van ZutvenMalgorzata Ilona SrebniakKarin Huijsdens-van AmsterdamJohn J M EngelenDominique SmeetsAnton H van KaamMartina C CornelPublished in: Prenatal diagnosis (2021)
Introducing NIPT did not change the decreasing trend in DS LB prevalence and increasing trend in reduction percentage. These trends may be caused by a broader development of more prenatal testing that had already started before introducing NIPT.
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