Influence of Tobacco Smoke Exposure on the Protein Expression of α7 and α4 Nicotinic Acetylcholine Receptors in Squamous Cell Carcinoma Tumors of the Upper Aerodigestive Tract (Out of the Larynx).
Bertha B Montaño-VelázquezJuan C Benavides MéndezFrancisco J García-VázquezErnesto Conde-VázquezMagdalena Sánchez-UribeCecilia R Taboada-MurrietaKathrine Jáuregui-RenaudPublished in: Substance abuse : research and treatment (2018)
Squamous cell carcinoma tumors of the upper aerodigestive tract (out of the larynx) may show desensitization of α4 nAChR. Advanced disease at diagnosis might be associated with desensitization of α4 with decrease in α7 nAChR.