Modelling Radiation-Induced Salivary Dysfunction during IMRT and Chemotherapy for Nasopharyngeal Cancer Patients.

Anna CavalloNicola Alessandro IacovelliNadia FacchinettiTiziana RancatiSalvatore AlfieriTommaso GiandiniAlessandro CicchettiCarlo FallaiRossana IngargiolaLisa LicitraLaura LocatiStefano CavalieriEmanuele PignoliDomenico Attilio RomanelloRiccardo ValdagniEster Orlandi

Published in: Cancers (2021)

cPG D98% and the high doses received by small OC volumes were found to have the most impact on grade ≥ 2 acute xerostomia, with age and smoking history acting as a dose-modifying factor. Findings on the development population were confirmed in two prospectively collected validation populations.

Keyphrases

radiation induced
radiation therapy
liver failure
respiratory failure
dna methylation
locally advanced
smoking cessation
oxidative stress
drug induced
aortic dissection
squamous cell carcinoma
intensive care unit
genetic diversity