Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
Shea J AndrewsBrian Fulton-HowardPaul F O'ReillyEdoardo MarcoraAlison Mary Goatenull nullPublished in: Annals of neurology (2020)
Our comprehensive examination of the genetic evidence for the causal relationships between previously reported risk factors in AD using PRS and MR supports a causal role for education, blood pressure, cholesterol levels, smoking, and diabetes with the AD phenome. ANN NEUROL 2021;89:54-65.