Placental DNA methylation changes in detection of tetralogy of Fallot.

R Bahado-SinghS VishweswaraiahN K MishraC GudaUppala Radhakrishna

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)

Analysis of placental DNA cytosine methylation changes yielded accurate markers for TOF detection and provided mechanistic information on TOF development. Our work appears to confirm the central role of epigenetic changes and of the placenta in the development of TOF. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

dna methylation
mass spectrometry
ms ms
genome wide
gene expression
loop mediated isothermal amplification
real time pcr
label free
high resolution
cell free
circulating tumor
healthcare
single molecule
quantum dots