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Molecular definition of severe acute respiratory syndrome coronavirus 2 receptor-binding domain mutations: Receptor affinity versus neutralization of receptor interaction.

Monique VogelGilles Sousa AugustoXinyue ChangXuelan LiuDaniel SpeiserMona O MohsenMartin F Bachmann
Published in: Allergy (2021)
Our data demonstrate that single mutations either affect receptor affinity or immune recognition while triple mutant RBDs combine both features.
Keyphrases
  • respiratory syndrome coronavirus
  • binding protein
  • coronavirus disease
  • mass spectrometry