Evidence of subclinical quantitative retinal layer abnormalities in AQP4-IgG seropositive NMOSD.
Angeliki G FilippatouEleni S VasileiouYufan HeKathryn C FitzgeraldGrigorios KalaitzidisJeffrey LambeMaureen A MealyMichael LevyYihao LiuJerry L PrinceEllen M MowryShiv SaidhaPeter A CalabresiElias S SotirchosPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)
AQP4-nonON eyes exhibit evidence of subclinical retinal ganglion cell neuronal and axonal loss, as well as structural evidence of photoreceptor layer involvement. These findings support that subclinical anterior visual pathway involvement may occur in AQP4-IgG+ NMOSD.