Proton pump inhibitor use and bone fractures in patients with chronic kidney disease.

Andreas KommerKarel KostevEva Maria SchleicherJulia Weinmann-Menke Christian Labenz

Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)

This study provides evidence that PPI use is associated with fractures in patients with CKD. Deprescription of PPI in patients without an indication for treatment could be a modifiable risk factor to reduce fracture risk in this high-risk group.

Keyphrases

end stage renal disease
chronic kidney disease
ejection fraction
risk factors
newly diagnosed
prognostic factors
peritoneal dialysis
bone mineral density
combination therapy
soft tissue
replacement therapy