NAFLD-related gene polymorphisms and all-cause and cause-specific mortality in an Asian population: the Shanghai Changfeng Study.

Ming-Feng XiaShuai MaQingxia HuangHailuan ZengJieyu GeWenjie XuQi WuLi WuXiaoming LiHui MaLingyan ChenQian LiQiqige AletengYu HuWanyuan HeBaishen PanHuandong LinYan ZhengSijia WangHuiru TangHuan-Dong Lin

Published in: Alimentary pharmacology & therapeutics (2022)

The PNPLA3 rs738409 C>G variant and its combination with TM6SF2 rs58542926 C>T and MBOAT7 rs641738 C>T variants increase liver-specific mortality but reduce cardiovascular mortality in overweight/obese Chinese.

Keyphrases

cardiovascular events
weight loss
adipose tissue
type diabetes
metabolic syndrome
physical activity
cardiovascular disease
gene expression
obese patients