Pharmacological targeting of Axin2 suppresses cell growth and metastasis in colorectal cancer.

Li-Zhi ChengDan-Ling HuangZhang-Rui TangJia-Hao ZhangTing XiongChen ZhouNai-Xia ZhangRong FuYong-Xian ChengZhao-Qiu Wu

Published in: British journal of pharmacology (2023)

These findings suggest that pharmacological targeting of Axin2 by CW85319 may provide therapeutic benefits against certain human cancers, especially CRCs.

Keyphrases

endothelial cells
cancer therapy
single cell
signaling pathway
cell therapy
induced pluripotent stem cells
drug delivery