Chromosome-mediated multidrug resistance in Salmonella enterica serovar Typhi.

Chien-Shun ChiouMunirul AlamJung-Che KuoYen-Yi LiuPei-Jen Wang

Published in: Antimicrobial agents and chemotherapy (2014)

A salmonella genomic island, designated SGI11, was found in 18 of 26 multidrug-resistant Salmonella enterica serovar Typhi isolates from Bangladesh. SGI11 was an IS1 composite transposon and carried 7 resistance genes that conferred resistance to 5 first-line antimicrobials. Eleven of the 18 SGI11-carrying S. Typhi isolates had developed resistance to high levels of ciprofloxacin.

Keyphrases

multidrug resistant
listeria monocytogenes
escherichia coli
copy number
pseudomonas aeruginosa
drug resistant
genome wide
gram negative
acinetobacter baumannii
cystic fibrosis