Genotype effects contribute to variation in longitudinal methylome patterns in older people.

Qian ZhangRiccardo E MarioniMatthew R RobinsonJon HighamDuncan SproulNaomi R WrayIan J DearyAllan F McRaePeter M Visscher

Published in: Genome medicine (2018)

We identified CpG sites that have variability in the rate of change of DNA methylation between individuals, and our results suggest a genetic basis of this variation. Genes around these CpG sites have been reported to be involved in the ageing process.

Keyphrases

dna methylation
genome wide
gene expression
copy number