Long-Read Nanopore Sequencing Identifies Mismatch Repair-Deficient Related Genes with Alternative Splicing in Colorectal Cancer.

Hao QuZhen-Jun Wang Yudong ZhangBaocheng ZhaoShuai JingJianwei ZhangChun-Xiang YeYaohan XueLei Yang

Published in: Disease markers (2022)

Our results showed that ONT-identified genes provide a pool to explore AS-associated markers for dMMR/MSI CRC. We demonstrated INHBA as a promising signature for clinical application in predicting tumor lymphatic metastasis and screening dMMR/MSI candidates.

Keyphrases

genome wide
single molecule
lymph node
dna methylation
single cell
bioinformatics analysis
genome wide identification
gene expression
solid state