Impact of Intestinal Bacteria on Levodopa Pharmacokinetics in LCIG Therapy.

Yuki YamanishiMohammed Emamussalehin ChoudhuryAkira YoshidaYuko HosokawaNoriyuki MiyaueSatoshi TadaRina AndoShinobu MurakamiHitoshi MiyamotoMasahiro Nagai

Published in: Movement disorders clinical practice (2022)

in the PEG-J tube. We observed levodopa metabolism in vitro, but there was no association with levodopa blood concentration. The effect of intestinal bacteria may be limited in patients receiving LCIG therapy.

Keyphrases

parkinson disease
deep brain stimulation
drug delivery
stem cells
bone marrow