Hyperglycemia accelerates inflammaging in the gingival epithelium through inflammasomes activation.

Peng ZhangBoyao LuRui ZhuDawei YangWeiqing LiuQian WangNing JiQianming ChenYi DingXing LiangQi Wang

Published in: Journal of periodontal research (2021)

Hyperglycemia accelerated inflammaging in the gingival epithelium through inflammasomes activation, which is potentially affiliated with a decline in the gingival epithelial barrier function in diabetes. Inflammasomes-related inflammaging may be the crucial mechanism underlying diabetic periodontitis and represents significant opportunities for advancing prevention and treatment options.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
wound healing
metabolic syndrome
oxidative stress
skeletal muscle
insulin resistance