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Vasodilatory Actions of Glucagon-Like Peptide 1 Are Preserved in Skeletal and Cardiac Muscle Microvasculature but Not in Conduit Artery in Obese Humans With Vascular Insulin Resistance.

Nasui WangAlvin W K TanLinda A JahnLee HartlineJames T PatrieShaoda LinEugene J BarrettKevin W AylorZhenqi Liu
Published in: Diabetes care (2019)
In obese humans with microvascular insulin resistance, GLP-1's vasodilatory actions are preserved in both skeletal and cardiac muscle microvasculature, which may contribute to improving metabolic insulin responses and cardiovascular outcomes.
Keyphrases
  • type diabetes
  • adipose tissue
  • insulin resistance
  • metabolic syndrome
  • skeletal muscle
  • weight loss
  • left ventricular
  • obese patients
  • glycemic control
  • high fat diet
  • polycystic ovary syndrome
  • atrial fibrillation