Patient-Derived Xenograft Models in Cervical Cancer: A Systematic Review.

Tomohito TanakaRuri NishieShoko UedaShunsuke MiyamotoSousuke HashidaHiromi KonishiShinichi TeradaYuhei KogataHiroshi SasakiSatoshi TsunetohKohei TaniguchiKazumasa KomuraMasahide Ohmichi

Published in: International journal of molecular sciences (2021)

Severe immunodeficient mice and subrenal capsule implantation led to a higher engraftment rate; however, orthotopic and subcutaneous implantation were alternatives. When using nude mice, subrenal implantation may be better. Fragments with a size of 1-3 mm3 were suitable for CC-PDX. Few reports have been published about CC-PDX; the results were not confirmed because of the small sample size.

Keyphrases

high fat diet induced
wild type
emergency department
type diabetes
metabolic syndrome