TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice.

Qiang LiWoo-Jin SongMin-Ok RyuAryung NamJu-Hyun AnJin-Ok AhnDong Ha BhangYun Chan JungHwa Young Youn

Published in: Stem cell research & therapy (2018)

TSG-6 secreted by hAT-MSCs protects PACs in SAP model mice via the inhibition of ER stress, as well as inflammatory responses. This study has revealed a new area for ER stress-targeted therapy in SAP patients.

Keyphrases

adipose tissue
end stage renal disease
high fat diet induced
endothelial cells
ejection fraction
mesenchymal stem cells
insulin resistance
prognostic factors
type diabetes
cell proliferation
high fat diet
early onset
single cell
skeletal muscle
metabolic syndrome
patient reported outcomes
patient reported