Smoking is associated with quantifiable differences in the human lung DNA virome and metabolome.
Ann C GregoryMatthew B SullivanLeopoldo N SegalBrian C KellerPublished in: Respiratory research (2018)
Our assessment of human lung DNA viral communities reveals that commensal viruses are present in the lower respiratory tract and differ between smokers and nonsmokers. The associations between viral populations and local immune and metabolic tone suggest a significant role for virome-host interaction in smoking related lung disease.