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Toll-like receptor-4 299Gly allele is associated with Guillain-Barré syndrome in Bangladesh.

Israt JahanRijwan U AhammadMir M KhalidMohammad I RahmanShoma HayatBadrul IslamQuazi D MohammadZhahirul Islam
Published in: Annals of clinical and translational neurology (2019)
The TLR4 minor 299Gly allele was associated with increased susceptibility to GBS and the axonal GBS subtype in the Bangladeshi population. However, no associations were observed between the genotypes of the Asp299Gly and Thr399Ile SNPs and antecedent C. jejuni infection or disease severity in Bangladeshi patients with GBS.
Keyphrases
  • toll like receptor
  • inflammatory response
  • nuclear factor
  • immune response
  • spinal cord injury
  • genome wide
  • case report
  • gene expression
  • dna methylation
  • optic nerve