A systematic review and meta-analysis of antibiotic-loaded bone cement for prevention of deep surgical site infections following primary total joint replacement.

Hideo KatoYukihiro HamadaShotaro TakanoShinsuke IkedaYoshinori SetoKazuhiko MatsushitaKoji YamadaKatsufumi Uchiyama

Published in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (2024)

Although the overall preventive effect of ALBC was significant, the evidence level was very low. Thus, the routine use of ALBC as a mean to prevent SSI in arthroplasty may not be suggested.

Keyphrases

surgical site infection
drug delivery
bone mineral density
clinical practice
cancer therapy
soft tissue
bone loss
bone regeneration
wound healing
postmenopausal women
body composition