Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese.
Yoshihiko TomofujiYuichi MaedaEri Oguro-IgashiraToshihiro KishikawaKenichi YamamotoKyuto SoneharaDaisuke MotookaYuki MatsumotoHidetoshi MatsuokaMaiko YoshimuraMayu YagitaTakuro NiiShiro OhshimaShota NakamuraHidenori InoharaKiyoshi TakedaAtsushi KumanogohYukinori OkadaPublished in: Annals of the rheumatic diseases (2021)
Our MWAS followed by integrative analysis revealed SLE-associated changes in the gut microbiome and its interaction with the host, which contribute to our understanding of the relationship between the microbiome and SLE.