Population Pharmacokinetics and Model-Based Dose Optimization of Vancomycin in Sudanese Adult Patients with Renal Impairment.

Khalid Altigani Awad Alkarem Ahmed Alnada Ibrahim Daniel Gonzalez Abubakr O Nur

Published in: Drug design, development and therapy (2024)

A population PK model of vancomycin was developed using data obtained from adult Sudanese patients. Model-based dose optimization can aid clinicians in selecting initial vancomycin doses that will maximize the likelihood of a favorable treatment response.

Keyphrases

methicillin resistant staphylococcus aureus
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
palliative care
peritoneal dialysis
staphylococcus aureus
big data
machine learning
patient reported