Impact of neutropenia evaluated in terms of the D-index on invasive fungal disease while on empiric or preemptive antifungal treatment strategy in the early phase after allogeneic hematopoietic stem cell transplantation.
Shun-Ichi KimuraYuhei NakamuraMasakatsu KawamuraJunko TakeshitaShunto KawamuraNozomu YoshinoYukiko MisakiKazuki YoshimuraShimpei MatsumiAyumi GomyoYu AkahoshiMasaharu TamakiMachiko KusudaKazuaki KamedaHidenori WadaMiki SatoKiriko Terasako-SaitoAki TaniharaHideki NakasoneShinichi KakoYoshinobu KandaPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
The appropriate CO value for the c-D-index for predicting IFD was as high as 10 644 in allogeneic HSCT with a more frequent use of empiric antifungal therapy. The c-D-index is useful for assessing the risk of breakthrough IFD.