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Accounting for grouped predictor variables or pathways in high-dimensional penalized Cox regression models.

Shaima BelhechmiRiccardo De BinFederico RotoloStefan Michiels
Published in: BMC bioinformatics (2020)
The adaptive lasso with the MSW*SW weighting method incorporates both the information in the grouping structure and the individual variable. It outperformed the competitors by reducing the false discovery rate without severely increasing the false negative rate.
Keyphrases
  • small molecule
  • high throughput
  • health information
  • municipal solid waste