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Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value.

Ana L CoutinhoRodrigo CristofolettiFang WuAbdullah Al ShoyaibJennifer DressmanJames E Polli
Published in: Pharmaceutical research (2024)
prediction of highly lipophilic drugs, suggesting BPR as a favorable surrogate for drug partitioning in the tissues, and which avoids the use of fup.
Keyphrases
  • drug induced
  • gene expression
  • emergency department