Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value.
Ana L CoutinhoRodrigo CristofolettiFang WuAbdullah Al ShoyaibJennifer DressmanJames E PolliPublished in: Pharmaceutical research (2024)
prediction of highly lipophilic drugs, suggesting BPR as a favorable surrogate for drug partitioning in the tissues, and which avoids the use of fup.