Immuno-PET of colorectal cancer with a CEA-targeted [68 Ga]Ga-nanobody: from bench to bedside.

Liqiang LiXinfeng LinLin WangXiaopan MaZiqing ZengFutao LiuBing JiaHua ZhuAiwen WuZhi Yang

Published in: European journal of nuclear medicine and molecular imaging (2023)

[68 Ga]Ga-HNI01 is a novel CEA-targeted PET imaging radiotracer with excellent pharmacokinetics and favorable dosimetry profiles. [68 Ga]Ga-HNI01 PET is an effective and convenient imaging tool for detecting CRC lesions, particularly for identifying small metastases. Furthermore, its high specificity for CEA in vivo makes it an ideal tool for selecting patients for anti-CEA therapy.

Keyphrases

pet ct
pet imaging
positron emission tomography
newly diagnosed
ejection fraction
mesenchymal stem cells
high resolution
cancer therapy
computed tomography
stem cells
prognostic factors
mass spectrometry
replacement therapy