Associations between circulating levels of Myostatin and plasma β⁃Amyloid 42/40 in a biracial cohort of older adults.
Brendan L McNeishIva MiljkovicXiaonan ZhuPeggy M CawthonAnne B NewmanBennett P GreenwoodKristine YaffeCaterina RosanoPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
Higher serum myostatin was associated with lower amyloid burden, independently of APOe4 alleles, muscle area and other established risk factors for dementia. The role of myostatin in AD pathogenesis, and the influence of race should be further investigated.