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Clinical outcomes of the entire papilla preservation technique with and without biomaterials in the treatment of isolated intrabony defects: A randomized controlled clinical trial.

Serhat AslanNurcan BuduneliPierpaolo Cortellini
Published in: Journal of clinical periodontology (2020)
Application of EPP with and without regenerative biomaterials resulted in significant amounts of CAL gain and PD reduction, with negligible increase in gingival recession. Within the limits of the present study, it can be concluded that the addition of regenerative biomaterials does not improve the clinical outcomes of EPP alone. NCT03923465.
Keyphrases
  • tissue engineering
  • stem cells
  • mesenchymal stem cells
  • cell therapy
  • bone regeneration
  • combination therapy
  • bone marrow