Anti-osteoporotic drug efficacy for periprosthetic bone loss after total hip arthroplasty: A systematic review and network meta-analysis.

Masaki HatanoYasuhiko KoizumiNorio YamamotoKota MiyoshiKensuke KawabataTakeyuki TanakaSakae TanakaAkihiro ShiroshitaYuki Kataoka

Published in: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association (2024)

Bisphosphonate and denosumab may be effective anti-osteoporotic drugs for preventing periprosthetic proximal femoral bone loss due to stress shielding after THA, particularly in cementless proximal fixation stems, which are the most commonly used prostheses worldwide.

Keyphrases

bone loss
total hip arthroplasty
bone mineral density
postmenopausal women
total hip
minimally invasive
body composition
emergency department
stress induced
giant cell
adverse drug