Adenosine deaminase 2 activity negatively correlates with age during childhood.
Sarah M BowersKristen M GibsonDavid A CabralKelly L BrownPublished in: Pediatric rheumatology online journal (2020)
We observed that ADA2 enzyme activity, but not ADA2 protein concentration, negatively correlates with age in a cohort of children and adolescents. Our findings stress the importance of appropriate age-matched controls for assessing ADA2 enzyme activity in the clinical setting.