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Levetiracetam as a first line antiseizure medication in WHO grade 2 glioma: time to seizure freedom and rates of treatment failure.

Sam FaircloughJohn GooddenPaul ChumasRyan MathewMelissa Maguire
Published in: Epilepsia (2023)
Over two-thirds of WHO grade 2 glioma patients treated with levetiracetam first line achieve seizure freedom within 2 years and it is a reasonable first choice agent. Experiencing mainly focal seizures without progression infers a significant long-term reduction in the chance of seizure freedom. Further studies are needed to inform ASM selection.
Keyphrases
  • temporal lobe epilepsy
  • healthcare
  • emergency department
  • adverse drug
  • decision making
  • combination therapy
  • case control