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An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes.

David PolakLior Shapira
Published in: Journal of clinical periodontology (2017)
The elevated pro-inflammatory factors in the gingiva of patients with poorly controlled diabetes suggest a biological pathway that may aggravate periodontitis. Some evidence suggests that the systemic inflammatory burden in periodontitis has the potential to affect diabetes control, but no studies addressed the impact of successful periodontal therapy on the pathophysiological mechanisms involved in systemic complications of diabetes.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • risk factors
  • stem cells
  • metabolic syndrome
  • climate change
  • risk assessment
  • skeletal muscle
  • weight loss
  • human health
  • replacement therapy