Identifying drug combinations associated with acute kidney injury using association rules method.

Published in: Pharmacoepidemiology and drug safety (2020)

We applied ARs, a novel methodology, to big data to ascertain drug combinations associated with AKI. ARs uncovered previously implicated medication classes that increase the risk of AKI in older adults. The finding that ondansetron increases the risk of AKI requires further investigation.

Keyphrases

acute kidney injury
big data
cardiac surgery
artificial intelligence
adverse drug
machine learning
physical activity
healthcare
drug induced
deep learning